LBH domain-containing protein 1 (LBHD1)
Homo sapiens — UniProt Q9BQE6
Data last refreshed: (UniProt release unknown)
Key facts
LBH domain-containing protein 1 (LBHD1) is a protein from Homo sapiens identified by UniProt accession Q9BQE6, 289 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9BQE6; gene symbol LBHD1.
- Organism: Homo sapiens.
- Length: 289 amino acids.
- Top disease associations (Open Targets): Isolated CoQ-cytochrome C reductase deficiency, blood protein measurement and resting heart rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | LBH domain-containing protein 1 |
|---|---|
| UniProt accession | Q9BQE6 |
| Gene | LBHD1 |
| Organism | Homo sapiens |
| Length | 289 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- Isolated CoQ-cytochrome C reductase deficiency · score 0.33
- blood protein measurement · score 0.28
- resting heart rate · score 0.15
- mean corpuscular hemoglobin concentration · score 0.15
- neutrophil percentage of leukocytes · score 0.13
- body fat percentage · score 0.12
- triglyceride measurement · score 0.08
- appendicular lean mass · score 0.08
- serum alanine aminotransferase measurement · score 0.07
- aspartate aminotransferase measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQE6-F1 | alphafold | PREDICTED | 49.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQE6.
Amino-acid sequence (289 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LBHD1?
The strongest Open Targets associations for LBHD1 are Isolated CoQ-cytochrome C reductase deficiency, blood protein measurement, resting heart rate, mean corpuscular hemoglobin concentration and neutrophil percentage of leukocytes.
How long is the LBHD1 protein?
The Homo sapiens LBHD1 protein (UniProt Q9BQE6) is 289 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQE6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQE6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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