B-cell CLL/lymphoma 7 protein family member B (BCL7B)
Homo sapiens — UniProt Q9BQE9
Data last refreshed: (UniProt release unknown)
Key facts
B-cell CLL/lymphoma 7 protein family member B (BCL7B) is a protein from Homo sapiens identified by UniProt accession Q9BQE9, 202 residues long. MolForge cross-references it against 0 known binders and 148 disease associations.
- UniProt accession: Q9BQE9; gene symbol BCL7B.
- Organism: Homo sapiens.
- Length: 202 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, BMI-adjusted waist-hip ratio and serum gamma-glutamyl transferase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | B-cell CLL/lymphoma 7 protein family member B |
|---|---|
| UniProt accession | Q9BQE9 |
| Gene | BCL7B |
| Organism | Homo sapiens |
| Length | 202 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (148)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.21
- BMI-adjusted waist-hip ratio · score 0.19
- serum gamma-glutamyl transferase measurement · score 0.18
- diastolic blood pressure · score 0.18
- physical activity measurement · score 0.16
- birth weight · score 0.16
- mean corpuscular volume · score 0.16
- protein C measurement · score 0.15
- coagulation factor measurement · score 0.15
- monocyte count · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQE9-F1 | alphafold | PREDICTED | 62.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQE9.
Amino-acid sequence (202 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BCL7B?
The strongest Open Targets associations for BCL7B are triglyceride measurement, BMI-adjusted waist-hip ratio, serum gamma-glutamyl transferase measurement, diastolic blood pressure and physical activity measurement.
How long is the BCL7B protein?
The Homo sapiens BCL7B protein (UniProt Q9BQE9) is 202 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQE9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQE9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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