Skip to content

Myb-binding protein 1A (MYBBP1A)

Homo sapiens — UniProt Q9BQG0

Gene: MYBBP1AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Myb-binding protein 1A (MYBBP1A) is a protein from Homo sapiens identified by UniProt accession Q9BQG0, 1328 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.

  • UniProt accession: Q9BQG0; gene symbol MYBBP1A.
  • Organism: Homo sapiens.
  • Length: 1328 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, endometrial cancer and lysosomal storage disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMyb-binding protein 1A
UniProt accessionQ9BQG0
GeneMYBBP1A
OrganismHomo sapiens
Length1328 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (101)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.51
  • endometrial cancer · score 0.21
  • lysosomal storage disease · score 0.19
  • Meniere disease · score 0.16
  • breast adenocarcinoma · score 0.11
  • autism · score 0.11
  • neoplasm · score 0.11
  • hepatocellular carcinoma · score 0.07
  • primary familial polycythemia due to EPO receptor mutation · score 0.06
  • renal carcinoma · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BQG0-F1alphafoldPREDICTED73.97—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQG0.

Amino-acid sequence (1328 residues)

MESRDPAQPM SPGEATQSGA RPADRYGLLK HSREFLDFFW DIAKPEQETR LAATEKLLEY LRGRPKGSEM KYALKRLITG LGVGRETARP CYSLALAQLL QSFEDLPLCS ILQQIQEKYD LHQVKKAMLR PALFANLFGV LALFQSGRLV KDQEALMKSV KLLQALAQYQ NHLQEQPRKA LVDILSEVSK ATLQEILPEV LKADLNIILS SPEQLELFLL AQQKVPSKLK KLVGSVNLFS DENVPRLVNV LKMAASSVKK DRKLPAIALD LLRLALKEDK FPRFWKEVVE QGLLKMQFWP ASYLCFRLLG AALPLLTKEQ LHLVMQGDVI RHYGEHVCTA KLPKQFKFAP EMDDYVGTFL EGCQDDPERQ LAVLVAFSSV TNQGLPVTPT FWRVVRFLSP PALQGYVAWL RAMFLQPDLD SLVDFSTNNQ KKAQDSSLHM PERAVFRLRK WIIFRLVSIV DSLHLEMEEA LTEQVARFCL FHSFFVTKKP TSQIPETKHP FSFPLENQAR EAVSSAFFSL LQTLSTQFKQ APGQTQGGQP WTYHLVQFAD LLLNHSHNVT TVTPFTAQQR QAWDRMLQTL KELEAHSAEA RAAAFQHLLL LVGIHLLKSP AESCDLLGDI QTCIRKSLGE KPRRSRTKTI DPQEPPWVEV LVEILLALLA QPSHLMRQVA RSVFGHICSH LTPRALQLIL DVLNPETSED ENDRVVVTDD SDERRLKGAE DKSEEGEDNR SSESEEESEG EESEEEERDG DVDQGFREQL MTVLQAGKAL GGEDSENEEE LGDEAMMALD QSLASLFAEQ KLRIQARRDE KNKLQKEKAL RRDFQIRVLD LVEVLVTKQP ENALVLELLE PLLSIIRRSL RSSSSKQEQD LLHKTARIFT HHLCRARRYC HDLGERAGAL HAQVERLVQQ AGRQPDSPTA LYHFNASLYL LRVLKGNTAE GCVHETQEKQ KAGTDPSHMP TGPQAASCLD LNLVTRVYST ALSSFLTKRN SPLTVPMFLS LFSRHPVLCQ SLLPILVQHI TGPVRPRHQA CLLLQKTLSM REVRSCFEDP EWKQLMGQVL AKVTENLRVL GEAQTKAQHQ QALSSLELLN VLFRTCKHEK LTLDLTVLLG VLQGQQQSLQ QGAHSTGSSR LHDLYWQAMK TLGVQRPKLE KKDAKEIPSA TQSPISKKRK KKGFLPETKK RKKRKSEDGT PAEDGTPAAT GGSQPPSMGR KKRNRTKAKV PAQANGTPTT KSPAPGAPTR SPSTPAKSPK LQKKNQKPSQ VNGAPGSPTE PAGQKQHQKA LPKKGVLGKS PLSALARKKA RLSLVIRSPS LLQSGAKKKA QVRKAGKP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MYBBP1A?

The strongest Open Targets associations for MYBBP1A are neurodegenerative disease, endometrial cancer, lysosomal storage disease, Meniere disease and breast adenocarcinoma.

How long is the MYBBP1A protein?

The Homo sapiens MYBBP1A protein (UniProt Q9BQG0) is 1328 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

Explore Myb-binding protein 1A with MolForge

Find binders, run structure-based screening, and map this target across diseases and approved drugs with our AI-powered platform.

Browse all targets

Quick facts

UniProtQ9BQG0
GeneMYBBP1A
OrganismHomo sapiens
Length1328
Binders0
Diseases101
View on UniProt