Synaptotagmin-3 (SYT3)
Homo sapiens — UniProt Q9BQG1
Data last refreshed: (UniProt release unknown)
Key facts
Synaptotagmin-3 (SYT3) is a protein from Homo sapiens identified by UniProt accession Q9BQG1, 590 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9BQG1; gene symbol SYT3.
- Organism: Homo sapiens.
- Length: 590 amino acids.
- Top disease associations (Open Targets): body mass index, smoking status measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptotagmin-3 |
|---|---|
| UniProt accession | Q9BQG1 |
| Gene | SYT3 |
| Organism | Homo sapiens |
| Length | 590 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- body mass index · score 0.40
- smoking status measurement · score 0.34
- body height · score 0.28
- carcinoma of liver and intrahepatic biliary tract · score 0.02
- Duane retraction syndrome · score 0.02
- Ataxia-telangiectasia · score 0.02
- gonorrhea · score 0.01
- laryngeal squamous cell carcinoma · score 0.01
- Stroke · score 0.01
- Lyme disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQG1-F1 | alphafold | PREDICTED | 68.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQG1.
Amino-acid sequence (590 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYT3?
The strongest Open Targets associations for SYT3 are body mass index, smoking status measurement, body height, carcinoma of liver and intrahepatic biliary tract and Duane retraction syndrome.
How long is the SYT3 protein?
The Homo sapiens SYT3 protein (UniProt Q9BQG1) is 590 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQG1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQG1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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