Allograft inflammatory factor 1-like (AIF1L)
Homo sapiens — UniProt Q9BQI0
Data last refreshed: (UniProt release unknown)
Key facts
Allograft inflammatory factor 1-like (AIF1L) is a protein from Homo sapiens identified by UniProt accession Q9BQI0, 150 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.
- UniProt accession: Q9BQI0; gene symbol AIF1L.
- Organism: Homo sapiens.
- Length: 150 amino acids.
- Top disease associations (Open Targets): mean platelet volume, neurodegenerative disease and oral cavity cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Allograft inflammatory factor 1-like |
|---|---|
| UniProt accession | Q9BQI0 |
| Gene | AIF1L |
| Organism | Homo sapiens |
| Length | 150 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (90)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.32
- neurodegenerative disease · score 0.31
- oral cavity cancer · score 0.07
- cortical thickness · score 0.07
- balding measurement · score 0.07
- breast cancer · score 0.06
- cortical surface area measurement · score 0.06
- neuroimaging measurement · score 0.05
- self reported educational attainment · score 0.05
- Obesity · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQI0-F1 | alphafold | PREDICTED | 84.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQI0.
Amino-acid sequence (150 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AIF1L?
The strongest Open Targets associations for AIF1L are mean platelet volume, neurodegenerative disease, oral cavity cancer, cortical thickness and balding measurement.
How long is the AIF1L protein?
The Homo sapiens AIF1L protein (UniProt Q9BQI0) is 150 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQI0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQI0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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