SMC5-SMC6 complex localization factor protein 1 (SLF1)
Homo sapiens — UniProt Q9BQI6
Data last refreshed: (UniProt release unknown)
Key facts
SMC5-SMC6 complex localization factor protein 1 (SLF1) is a protein from Homo sapiens identified by UniProt accession Q9BQI6, 1058 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9BQI6; gene symbol SLF1.
- Organism: Homo sapiens.
- Length: 1058 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, cortical thickness and neuroimaging measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SMC5-SMC6 complex localization factor protein 1 |
|---|---|
| UniProt accession | Q9BQI6 |
| Gene | SLF1 |
| Organism | Homo sapiens |
| Length | 1058 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.43
- cortical thickness · score 0.37
- neuroimaging measurement · score 0.36
- cortical surface area measurement · score 0.29
- brain measurement · score 0.29
- emotional symptom measurement · score 0.28
- language measurement · score 0.25
- functional brain measurement · score 0.25
- mathematical ability · score 0.15
- BMI-adjusted waist circumference · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQI6-F1 | alphafold | PREDICTED | 69.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQI6.
Amino-acid sequence (1058 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLF1?
The strongest Open Targets associations for SLF1 are self reported educational attainment, cortical thickness, neuroimaging measurement, cortical surface area measurement and brain measurement.
How long is the SLF1 protein?
The Homo sapiens SLF1 protein (UniProt Q9BQI6) is 1058 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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