Nuclear receptor-interacting protein 2 (NRIP2)
Homo sapiens — UniProt Q9BQI9
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear receptor-interacting protein 2 (NRIP2) is a protein from Homo sapiens identified by UniProt accession Q9BQI9, 281 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9BQI9; gene symbol NRIP2.
- Organism: Homo sapiens.
- Length: 281 amino acids.
- Target class: Nuclear receptor.
- Top disease associations (Open Targets): neurodegenerative disease, erythrocyte count and schizophrenia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear receptor-interacting protein 2 |
|---|---|
| UniProt accession | Q9BQI9 |
| Gene | NRIP2 |
| Organism | Homo sapiens |
| Length | 281 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Nuclear receptor (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- erythrocyte count · score 0.06
- schizophrenia · score 0.06
- hematocrit · score 0.06
- heel bone mineral density · score 0.06
- hemoglobin measurement · score 0.06
- platelet count · score 0.06
- bipolar disorder · score 0.05
- red blood cell density measurement · score 0.05
- platelet crit · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQI9-F1 | alphafold | PREDICTED | 66.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQI9.
Amino-acid sequence (281 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NRIP2?
The strongest Open Targets associations for NRIP2 are neurodegenerative disease, erythrocyte count, schizophrenia, hematocrit and heel bone mineral density.
How long is the NRIP2 protein?
The Homo sapiens NRIP2 protein (UniProt Q9BQI9) is 281 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQI9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQI9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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