Calsyntenin-3 (CLSTN3)
Homo sapiens — UniProt Q9BQT9
Data last refreshed: (UniProt release unknown)
Key facts
Calsyntenin-3 (CLSTN3) is a protein from Homo sapiens identified by UniProt accession Q9BQT9, 956 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.
- UniProt accession: Q9BQT9; gene symbol CLSTN3.
- Organism: Homo sapiens.
- Length: 956 amino acids.
- Top disease associations (Open Targets): autism spectrum disorder, neurodegenerative disease and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calsyntenin-3 |
|---|---|
| UniProt accession | Q9BQT9 |
| Gene | CLSTN3 |
| Organism | Homo sapiens |
| Length | 956 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (92)
Diseases linked to this target (Open Targets).
- autism spectrum disorder · score 0.33
- neurodegenerative disease · score 0.29
- blood protein measurement · score 0.19
- total blood protein measurement · score 0.18
- platelet crit · score 0.13
- complement C1s subcomponent measurement · score 0.09
- Young adult-onset Parkinsonism · score 0.05
- platelet count · score 0.05
- Spinocerebellar ataxia type 40 · score 0.05
- spinocerebellar ataxia type 20 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQT9-F1 | alphafold | PREDICTED | 77.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQT9.
Amino-acid sequence (956 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLSTN3?
The strongest Open Targets associations for CLSTN3 are autism spectrum disorder, neurodegenerative disease, blood protein measurement, total blood protein measurement and platelet crit.
How long is the CLSTN3 protein?
The Homo sapiens CLSTN3 protein (UniProt Q9BQT9) is 956 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQT9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQT9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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