Transcription factor COE4 (EBF4)
Homo sapiens — UniProt Q9BQW3
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor COE4 (EBF4) is a protein from Homo sapiens identified by UniProt accession Q9BQW3, 602 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q9BQW3; gene symbol EBF4.
- Organism: Homo sapiens.
- Length: 602 amino acids.
- Top disease associations (Open Targets): blood protein measurement, colorectal cancer and gonorrhea.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor COE4 |
|---|---|
| UniProt accession | Q9BQW3 |
| Gene | EBF4 |
| Organism | Homo sapiens |
| Length | 602 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.30
- colorectal cancer · score 0.01
- gonorrhea · score 0.01
- major depressive disorder · score 0.01
- juvenile idiopathic arthritis · score 0.00
- endometrial carcinoma · score 0.00
- cancer · score 0.00
- neoplasm · score 0.00
- infectious disease · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQW3-F1 | alphafold | PREDICTED | 70.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQW3.
Amino-acid sequence (602 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EBF4?
The strongest Open Targets associations for EBF4 are blood protein measurement, colorectal cancer, gonorrhea, major depressive disorder and juvenile idiopathic arthritis.
How long is the EBF4 protein?
The Homo sapiens EBF4 protein (UniProt Q9BQW3) is 602 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQW3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQW3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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