Rhox homeobox family member 2 (RHOXF2)

About Rhox homeobox family member 2

Rhox homeobox family member 2 (RHOXF2) is a protein from Homo sapiens identified by UniProt accession Q9BQY4, 288 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Rhox homeobox family member 2
UniProt accession	Q9BQY4
Gene	RHOXF2
Organism	Homo sapiens
Length	288 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
mental or behavioural disorder · score 0.09
alcohol-related disorders · score 0.09
cancer · score 0.03
triple-negative breast cancer · score 0.03
non-small cell lung carcinoma · score 0.02
Fibroadenoma · score 0.01
azoospermia · score 0.01
chronic myelogenous leukemia · score 0.01
multiple myeloma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BQY4-F1	alphafold	PREDICTED	62.93	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQY4.

Amino-acid sequence (288 residues)

MEPPDQCSQY MTSLLSPAVD DEKELQDMNA MVLSLTEEVK EEEEDAQPEP EQGTAAGEKL KSAGAQGGEE KDGGGEEKDG GGAGVPGHLW EGDLEGTSGS DGNVEDSDQS EKEPGQQYSR PQGAVGGLEP GNAQQPNVHA FTPLQLQELE RIFQREQFPS EFLRRRLARS MNVTELAVQI WFENRRAKWR RHQRALMARN MLPFMAVGQP VMVTAAEAIT APLFISGMRD DYFWDHSHSS SLCFPMPPFP PPSLPLPLML LPPMPPAGQA EFGPFPFVIV PSFTFPNV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards