Rhox homeobox family member 2 (RHOXF2)
Homo sapiens — UniProt Q9BQY4
Data last refreshed: (UniProt release unknown)
Key facts
Rhox homeobox family member 2 (RHOXF2) is a protein from Homo sapiens identified by UniProt accession Q9BQY4, 288 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9BQY4; gene symbol RHOXF2.
- Organism: Homo sapiens.
- Length: 288 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mental or behavioural disorder and alcohol-related disorders.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rhox homeobox family member 2 |
|---|---|
| UniProt accession | Q9BQY4 |
| Gene | RHOXF2 |
| Organism | Homo sapiens |
| Length | 288 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- mental or behavioural disorder · score 0.09
- alcohol-related disorders · score 0.09
- cancer · score 0.03
- triple-negative breast cancer · score 0.03
- non-small cell lung carcinoma · score 0.02
- Fibroadenoma · score 0.01
- azoospermia · score 0.01
- chronic myelogenous leukemia · score 0.01
- multiple myeloma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQY4-F1 | alphafold | PREDICTED | 62.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQY4.
Amino-acid sequence (288 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RHOXF2?
The strongest Open Targets associations for RHOXF2 are neurodegenerative disease, mental or behavioural disorder, alcohol-related disorders, cancer and triple-negative breast cancer.
How long is the RHOXF2 protein?
The Homo sapiens RHOXF2 protein (UniProt Q9BQY4) is 288 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQY4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQY4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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