Dysbindin domain-containing protein 2 (DBNDD2)
Homo sapiens — UniProt Q9BQY9
Data last refreshed: (UniProt release unknown)
Key facts
Dysbindin domain-containing protein 2 (DBNDD2) is a protein from Homo sapiens identified by UniProt accession Q9BQY9, 259 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9BQY9; gene symbol DBNDD2.
- Organism: Homo sapiens.
- Length: 259 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, FEV/FVC ratio and tibial hemimelia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dysbindin domain-containing protein 2 |
|---|---|
| UniProt accession | Q9BQY9 |
| Gene | DBNDD2 |
| Organism | Homo sapiens |
| Length | 259 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- FEV/FVC ratio · score 0.10
- tibial hemimelia · score 0.03
- acheiropody · score 0.03
- Fuhrmann syndrome · score 0.03
- acromesomelic dysplasia 2A · score 0.03
- acromesomelic dysplasia 2C, Hunter-Thompson type · score 0.03
- Acromesomelic dysplasia, Hunter-Thomson type · score 0.03
- acromesomelic dysplasia 3 · score 0.03
- glioblastoma multiforme · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BQY9-F1 | alphafold | PREDICTED | 59.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BQY9.
Amino-acid sequence (259 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DBNDD2?
The strongest Open Targets associations for DBNDD2 are neurodegenerative disease, FEV/FVC ratio, tibial hemimelia, acheiropody and Fuhrmann syndrome.
How long is the DBNDD2 protein?
The Homo sapiens DBNDD2 protein (UniProt Q9BQY9) is 259 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BQY9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BQY9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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