Spermatogenesis-associated protein 25 (SPATA25)
Homo sapiens — UniProt Q9BR10
Data last refreshed: (UniProt release unknown)
Key facts
Spermatogenesis-associated protein 25 (SPATA25) is a protein from Homo sapiens identified by UniProt accession Q9BR10, 227 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q9BR10; gene symbol SPATA25.
- Organism: Homo sapiens.
- Length: 227 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, alcohol drinking and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Spermatogenesis-associated protein 25 |
|---|---|
| UniProt accession | Q9BR10 |
| Gene | SPATA25 |
| Organism | Homo sapiens |
| Length | 227 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.03
- alcohol drinking · score 0.02
- triglyceride measurement · score 0.02
- Azoospermia · score 0.01
- breast cancer · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BR10-F1 | alphafold | PREDICTED | 56.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BR10.
Amino-acid sequence (227 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPATA25?
The strongest Open Targets associations for SPATA25 are alkaline phosphatase measurement, alcohol drinking, triglyceride measurement, Azoospermia and breast cancer.
How long is the SPATA25 protein?
The Homo sapiens SPATA25 protein (UniProt Q9BR10) is 227 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BR10 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BR10 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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