Osteoclast stimulatory transmembrane protein (OCSTAMP)
Homo sapiens — UniProt Q9BR26
Data last refreshed: (UniProt release unknown)
Key facts
Osteoclast stimulatory transmembrane protein (OCSTAMP) is a protein from Homo sapiens identified by UniProt accession Q9BR26, 566 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9BR26; gene symbol OCSTAMP.
- Organism: Homo sapiens.
- Length: 566 amino acids.
- Top disease associations (Open Targets): serum metabolite measurement, metabolite measurement and MODY.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Osteoclast stimulatory transmembrane protein |
|---|---|
| UniProt accession | Q9BR26 |
| Gene | OCSTAMP |
| Organism | Homo sapiens |
| Length | 566 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.10
- metabolite measurement · score 0.07
- MODY · score 0.05
- neutropenia-monocytopenia-deafness syndrome · score 0.05
- diabetes mellitus, permanent neonatal 4 · score 0.05
- diabetes mellitus, transient neonatal, 3 · score 0.04
- sitting height measurement · score 0.04
- hyperinsulinism due to INSR deficiency · score 0.04
- permanent neonatal diabetes mellitus 1 · score 0.04
- 3-hydroxy-3-methylglutaryl-CoA synthase deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BR26-F1 | alphafold | PREDICTED | 74.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BR26.
Amino-acid sequence (566 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OCSTAMP?
The strongest Open Targets associations for OCSTAMP are serum metabolite measurement, metabolite measurement, MODY, neutropenia-monocytopenia-deafness syndrome and diabetes mellitus, permanent neonatal 4.
How long is the OCSTAMP protein?
The Homo sapiens OCSTAMP protein (UniProt Q9BR26) is 566 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BR26 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BR26 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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