Acyl-CoA-binding domain-containing protein 6 (ACBD6)
Homo sapiens — UniProt Q9BR61
Data last refreshed: (UniProt release unknown)
Key facts
Acyl-CoA-binding domain-containing protein 6 (ACBD6) is a protein from Homo sapiens identified by UniProt accession Q9BR61, 282 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9BR61; gene symbol ACBD6.
- Organism: Homo sapiens.
- Length: 282 amino acids.
- Top disease associations (Open Targets): short stature-pituitary and cerebellar defects-small sella turcica syndrome, Combined pituitary hormone deficiencies, genetic forms and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Acyl-CoA-binding domain-containing protein 6 |
|---|---|
| UniProt accession | Q9BR61 |
| Gene | ACBD6 |
| Organism | Homo sapiens |
| Length | 282 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- short stature-pituitary and cerebellar defects-small sella turcica syndrome · score 0.51
- Combined pituitary hormone deficiencies, genetic forms · score 0.51
- Intellectual disability · score 0.33
- brain measurement · score 0.22
- genetic disorder · score 0.19
- mathematical ability · score 0.18
- cortical thickness · score 0.14
- cortical surface area measurement · score 0.12
- pituitary hormone deficiency, combined, 1 · score 0.11
- chronotype measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BR61-F1 | alphafold | PREDICTED | 77.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BR61.
Amino-acid sequence (282 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACBD6?
The strongest Open Targets associations for ACBD6 are short stature-pituitary and cerebellar defects-small sella turcica syndrome, Combined pituitary hormone deficiencies, genetic forms, Intellectual disability, brain measurement and genetic disorder.
How long is the ACBD6 protein?
The Homo sapiens ACBD6 protein (UniProt Q9BR61) is 282 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BR61 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BR61 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.