Zinc finger protein 559 (ZNF559)
Homo sapiens — UniProt Q9BR84
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 559 (ZNF559) is a protein from Homo sapiens identified by UniProt accession Q9BR84, 538 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9BR84; gene symbol ZNF559.
- Organism: Homo sapiens.
- Length: 538 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, genetic disorder and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 559 |
|---|---|
| UniProt accession | Q9BR84 |
| Gene | ZNF559 |
| Organism | Homo sapiens |
| Length | 538 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.17
- genetic disorder · score 0.12
- appendicular lean mass · score 0.07
- neutrophil count · score 0.06
- serum gamma-glutamyl transferase measurement · score 0.05
- Ataxia-telangiectasia · score 0.01
- oligodendroglioma · score 0.01
- psoriasis · score 0.01
- chronic kidney disease · score 0.01
- breast carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BR84-F1 | alphafold | PREDICTED | 63.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BR84.
Amino-acid sequence (538 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF559?
The strongest Open Targets associations for ZNF559 are neurodegenerative disease, genetic disorder, appendicular lean mass, neutrophil count and serum gamma-glutamyl transferase measurement.
How long is the ZNF559 protein?
The Homo sapiens ZNF559 protein (UniProt Q9BR84) is 538 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BR84 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BR84 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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