Protein cholesin (CHLSN)
Homo sapiens — UniProt Q9BRJ6
Data last refreshed: (UniProt release unknown)
Key facts
Protein cholesin (CHLSN) is a protein from Homo sapiens identified by UniProt accession Q9BRJ6, 194 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9BRJ6; gene symbol CHLSN.
- Organism: Homo sapiens.
- Length: 194 amino acids.
- Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, total cholesterol measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein cholesin |
|---|---|
| UniProt accession | Q9BRJ6 |
| Gene | CHLSN |
| Organism | Homo sapiens |
| Length | 194 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.27
- total cholesterol measurement · score 0.26
- mean corpuscular volume · score 0.23
- high density lipoprotein cholesterol measurement · score 0.22
- systolic blood pressure · score 0.21
- mean corpuscular hemoglobin concentration · score 0.21
- reticulocyte count · score 0.21
- mean corpuscular hemoglobin · score 0.20
- diastolic blood pressure · score 0.20
- sex hormone-binding globulin measurement · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRJ6-F1 | alphafold | PREDICTED | 73.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRJ6.
Amino-acid sequence (194 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHLSN?
The strongest Open Targets associations for CHLSN are low density lipoprotein cholesterol measurement, total cholesterol measurement, mean corpuscular volume, high density lipoprotein cholesterol measurement and systolic blood pressure.
How long is the CHLSN protein?
The Homo sapiens CHLSN protein (UniProt Q9BRJ6) is 194 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRJ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRJ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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