Tudor-interacting repair regulator protein (NUDT16L1)
Homo sapiens — UniProt Q9BRJ7
Data last refreshed: (UniProt release unknown)
Key facts
Tudor-interacting repair regulator protein (NUDT16L1) is a protein from Homo sapiens identified by UniProt accession Q9BRJ7, 211 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.
- UniProt accession: Q9BRJ7; gene symbol NUDT16L1.
- Organism: Homo sapiens.
- Length: 211 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and multiple sclerosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tudor-interacting repair regulator protein |
|---|---|
| UniProt accession | Q9BRJ7 |
| Gene | NUDT16L1 |
| Organism | Homo sapiens |
| Length | 211 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.12
- Alzheimer disease · score 0.12
- multiple sclerosis · score 0.12
- Parkinson disease · score 0.12
- lysosomal storage disease · score 0.12
- body height · score 0.11
- pulse pressure measurement · score 0.11
- essential hypertension · score 0.06
- C-C motif chemokine 3 measurement · score 0.05
- isolated asymptomatic elevation of creatine phosphokinase · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRJ7-F1 | alphafold | PREDICTED | 93.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRJ7.
Amino-acid sequence (211 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NUDT16L1?
The strongest Open Targets associations for NUDT16L1 are neurodegenerative disease, Alzheimer disease, multiple sclerosis, Parkinson disease and lysosomal storage disease.
How long is the NUDT16L1 protein?
The Homo sapiens NUDT16L1 protein (UniProt Q9BRJ7) is 211 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRJ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRJ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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