Mesoderm posterior protein 1 (MESP1)
Homo sapiens — UniProt Q9BRJ9
Data last refreshed: (UniProt release unknown)
Key facts
Mesoderm posterior protein 1 (MESP1) is a protein from Homo sapiens identified by UniProt accession Q9BRJ9, 268 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9BRJ9; gene symbol MESP1.
- Organism: Homo sapiens.
- Length: 268 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, congenital heart disease and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mesoderm posterior protein 1 |
|---|---|
| UniProt accession | Q9BRJ9 |
| Gene | MESP1 |
| Organism | Homo sapiens |
| Length | 268 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- congenital heart disease · score 0.12
- reticulocyte count · score 0.12
- non-small cell lung carcinoma · score 0.08
- electrocardiography · score 0.07
- cancer · score 0.07
- neoplasm · score 0.04
- intraocular pressure measurement · score 0.03
- myocardial infarction · score 0.03
- hepatocellular carcinoma · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRJ9-F1 | alphafold | PREDICTED | 61.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRJ9.
Amino-acid sequence (268 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MESP1?
The strongest Open Targets associations for MESP1 are neurodegenerative disease, congenital heart disease, reticulocyte count, non-small cell lung carcinoma and electrocardiography.
How long is the MESP1 protein?
The Homo sapiens MESP1 protein (UniProt Q9BRJ9) is 268 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRJ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRJ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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