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uS5 assembly chaperone PDCD2L (PDCD2L)

Homo sapiens — UniProt Q9BRP1

Gene: PDCD2LHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

uS5 assembly chaperone PDCD2L (PDCD2L) is a protein from Homo sapiens identified by UniProt accession Q9BRP1, 358 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

  • UniProt accession: Q9BRP1; gene symbol PDCD2L.
  • Organism: Homo sapiens.
  • Length: 358 amino acids.
  • Top disease associations (Open Targets): mean corpuscular volume, cancer and mean corpuscular hemoglobin.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameuS5 assembly chaperone PDCD2L
UniProt accessionQ9BRP1
GenePDCD2L
OrganismHomo sapiens
Length358 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (40)

Diseases linked to this target (Open Targets).

  • mean corpuscular volume · score 0.09
  • cancer · score 0.08
  • mean corpuscular hemoglobin · score 0.07
  • mean reticulocyte volume · score 0.07
  • acute myeloid leukemia · score 0.06
  • renal cell carcinoma · score 0.04
  • pulse pressure measurement · score 0.04
  • electrocardiography · score 0.03
  • neoplasm · score 0.03
  • pachyonychia congenita · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BRP1-F1alphafoldPREDICTED75.45—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRP1.

Amino-acid sequence (358 residues)

MAAVLKPVLL GLRDAPVHGS PTGPGAWTAS KLGGIPDALP TVAAPRPVCQ RCGQPLALVV QVYCPLEGSP FHRLLHVFAC ACPGCSTGGA RSWKVFRSQC LQVPEREAQD AQKQGNSLAA EDWCEGADDW GSDTEEGPSP QFTLDFGNDA SSAKDVDWTA RLQDLRLQDA VLGAAHPVPP GLPLFLPYYI CVADEDDYRD FVNLDHAHSL LRDYQQREGI AMDQLLSQSL PNDGDEKYEK TIIKSGDQTF YKFMKRIAAC QEQILRYSWS GEPLFLTCPT SEVTELPACS QCGGQRIFEF QLMPALVSML KSANLGLSVE FGTILVYTCE KSCWPPNHQT PMEEFCIIQE DPDELLFK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PDCD2L?

The strongest Open Targets associations for PDCD2L are mean corpuscular volume, cancer, mean corpuscular hemoglobin, mean reticulocyte volume and acute myeloid leukemia.

How long is the PDCD2L protein?

The Homo sapiens PDCD2L protein (UniProt Q9BRP1) is 358 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BRP1
GenePDCD2L
OrganismHomo sapiens
Length358
Binders0
Diseases40
View on UniProt