Partner of Y14 and mago (PYM1)
Homo sapiens — UniProt Q9BRP8
Data last refreshed: (UniProt release unknown)
Key facts
Partner of Y14 and mago (PYM1) is a protein from Homo sapiens identified by UniProt accession Q9BRP8, 204 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9BRP8; gene symbol PYM1.
- Organism: Homo sapiens.
- Length: 204 amino acids.
- Top disease associations (Open Targets): cancer, Sjogren syndrome and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Partner of Y14 and mago |
|---|---|
| UniProt accession | Q9BRP8 |
| Gene | PYM1 |
| Organism | Homo sapiens |
| Length | 204 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- cancer · score 0.02
- Sjogren syndrome · score 0.02
- neoplasm · score 0.02
- hepatocellular carcinoma · score 0.02
- Rheumatoid arthritis · score 0.01
- hemangioma · score 0.01
- oral squamous cell carcinoma · score 0.01
- ulcerative colitis · score 0.01
- viral disease · score 0.01
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRP8-F1 | alphafold | PREDICTED | 73.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRP8.
Amino-acid sequence (204 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PYM1?
The strongest Open Targets associations for PYM1 are cancer, Sjogren syndrome, neoplasm, hepatocellular carcinoma and Rheumatoid arthritis.
How long is the PYM1 protein?
The Homo sapiens PYM1 protein (UniProt Q9BRP8) is 204 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRP8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRP8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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