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Uridine diphosphate glucose pyrophosphatase NUDT22 (NUDT22)

Homo sapiens — UniProt Q9BRQ3

Gene: NUDT22Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uridine diphosphate glucose pyrophosphatase NUDT22 (NUDT22) is a protein from Homo sapiens identified by UniProt accession Q9BRQ3, 303 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

  • UniProt accession: Q9BRQ3; gene symbol NUDT22.
  • Organism: Homo sapiens.
  • Length: 303 amino acids.
  • Top disease associations (Open Targets): cancer, reticulocyte count and platelet count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUridine diphosphate glucose pyrophosphatase NUDT22
UniProt accessionQ9BRQ3
GeneNUDT22
OrganismHomo sapiens
Length303 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (16)

Diseases linked to this target (Open Targets).

  • cancer · score 0.07
  • reticulocyte count · score 0.05
  • platelet count · score 0.05
  • diet measurement · score 0.04
  • mean platelet volume · score 0.04
  • mean corpuscular volume · score 0.04
  • monocyte count · score 0.04
  • mean corpuscular hemoglobin · score 0.03
  • lymphocyte count · score 0.03
  • cognitive function measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BRQ3-F1alphafoldPREDICTED92.79—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRQ3.

Amino-acid sequence (303 residues)

MDPEVTLLLQ CPGGGLPQEQ IQAELSPAHD RRPLPGGDEA ITAIWETRLK AQPWLFDAPK FRLHSATLAP IGSRGPQLLL RLGLTSYRDF LGTNWSSSAA WLRQQGATDW GDTQAYLADP LGVGAALATA DDFLVFLRRS RQVAEAPGLV DVPGGHPEPQ ALCPGGSPQH QDLAGQLVVH ELFSSVLQEI CDEVNLPLLT LSQPLLLGIA RNETSAGRAS AEFYVQCSLT SEQVRKHYLS GGPEAHESTG IFFVETQNVQ RLLETEMWAE LCPSAKGAII LYNRVQGSPT GAALGSPALL PPL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NUDT22?

The strongest Open Targets associations for NUDT22 are cancer, reticulocyte count, platelet count, diet measurement and mean platelet volume.

How long is the NUDT22 protein?

The Homo sapiens NUDT22 protein (UniProt Q9BRQ3) is 303 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BRQ3
GeneNUDT22
OrganismHomo sapiens
Length303
Binders0
Diseases16
View on UniProt