MICOS complex subunit MIC25 (CHCHD6)
Homo sapiens — UniProt Q9BRQ6
Data last refreshed: (UniProt release unknown)
Key facts
MICOS complex subunit MIC25 (CHCHD6) is a protein from Homo sapiens identified by UniProt accession Q9BRQ6, 235 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9BRQ6; gene symbol CHCHD6.
- Organism: Homo sapiens.
- Length: 235 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, bilirubin measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MICOS complex subunit MIC25 |
|---|---|
| UniProt accession | Q9BRQ6 |
| Gene | CHCHD6 |
| Organism | Homo sapiens |
| Length | 235 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.24
- bilirubin measurement · score 0.10
- platelet count · score 0.05
- metabolite measurement · score 0.05
- glycine measurement · score 0.04
- skin aging · score 0.04
- skin aging measurement · score 0.03
- platelet crit · score 0.03
- Cognitive impairment · score 0.02
- blood protein measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRQ6-F1 | alphafold | PREDICTED | 78.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRQ6.
Amino-acid sequence (235 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHCHD6?
The strongest Open Targets associations for CHCHD6 are neurodegenerative disease, bilirubin measurement, platelet count, metabolite measurement and glycine measurement.
How long is the CHCHD6 protein?
The Homo sapiens CHCHD6 protein (UniProt Q9BRQ6) is 235 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRQ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRQ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.