Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3)
Homo sapiens — UniProt Q9BRR0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) is a protein from Homo sapiens identified by UniProt accession Q9BRR0, 538 residues long. MolForge cross-references it against 0 known binders and 140 disease associations.
- UniProt accession: Q9BRR0; gene symbol ZKSCAN3.
- Organism: Homo sapiens.
- Length: 538 amino acids.
- Top disease associations (Open Targets): urate measurement, mean corpuscular volume and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein with KRAB and SCAN domains 3 |
|---|---|
| UniProt accession | Q9BRR0 |
| Gene | ZKSCAN3 |
| Organism | Homo sapiens |
| Length | 538 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (140)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.14
- mean corpuscular volume · score 0.14
- reticulocyte count · score 0.13
- platelet count · score 0.11
- lymphocyte count · score 0.11
- neutrophil percentage of leukocytes · score 0.11
- ankylosing spondylitis · score 0.10
- hepatocellular carcinoma · score 0.09
- neoplasm · score 0.08
- peak expiratory flow · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRR0-F1 | alphafold | PREDICTED | 59.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRR0.
Amino-acid sequence (538 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZKSCAN3?
The strongest Open Targets associations for ZKSCAN3 are urate measurement, mean corpuscular volume, reticulocyte count, platelet count and lymphocyte count.
How long is the ZKSCAN3 protein?
The Homo sapiens ZKSCAN3 protein (UniProt Q9BRR0) is 538 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRR0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRR0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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