ADP-dependent glucokinase (ADPGK)
Homo sapiens — UniProt Q9BRR6
Data last refreshed: (UniProt release unknown)
Key facts
ADP-dependent glucokinase (ADPGK) is a protein from Homo sapiens identified by UniProt accession Q9BRR6, 497 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q9BRR6; gene symbol ADPGK.
- Organism: Homo sapiens.
- Length: 497 amino acids.
- Top disease associations (Open Targets): body mass index, vital capacity and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-dependent glucokinase |
|---|---|
| UniProt accession | Q9BRR6 |
| Gene | ADPGK |
| Organism | Homo sapiens |
| Length | 497 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- body mass index · score 0.29
- vital capacity · score 0.16
- body fat percentage · score 0.15
- physical activity measurement · score 0.15
- grip strength measurement · score 0.15
- lean body mass · score 0.14
- body height · score 0.13
- fat body mass · score 0.12
- visceral adipose tissue measurement · score 0.11
- neoplasm · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRR6-F1 | alphafold | PREDICTED | 91.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRR6.
Amino-acid sequence (497 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADPGK?
The strongest Open Targets associations for ADPGK are body mass index, vital capacity, body fat percentage, physical activity measurement and grip strength measurement.
How long is the ADPGK protein?
The Homo sapiens ADPGK protein (UniProt Q9BRR6) is 497 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRR6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRR6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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