Ubiquinol-cytochrome c reductase complex assembly factor 2 (UQCC2)
Homo sapiens — UniProt Q9BRT2
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquinol-cytochrome c reductase complex assembly factor 2 (UQCC2) is a protein from Homo sapiens identified by UniProt accession Q9BRT2, 126 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.
- UniProt accession: Q9BRT2; gene symbol UQCC2.
- Organism: Homo sapiens.
- Length: 126 amino acids.
- Top disease associations (Open Targets): Isolated CoQ-cytochrome C reductase deficiency, neurodegenerative disease and celiac disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquinol-cytochrome c reductase complex assembly factor 2 |
|---|---|
| UniProt accession | Q9BRT2 |
| Gene | UQCC2 |
| Organism | Homo sapiens |
| Length | 126 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (103)
Diseases linked to this target (Open Targets).
- Isolated CoQ-cytochrome C reductase deficiency · score 0.72
- neurodegenerative disease · score 0.36
- celiac disease · score 0.32
- eosinophil percentage of leukocytes · score 0.32
- multiple sclerosis · score 0.28
- Alzheimer disease · score 0.27
- lysosomal storage disease · score 0.27
- Parkinson disease · score 0.27
- eosinophil count · score 0.24
- platelet count · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRT2-F1 | alphafold | PREDICTED | 88.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRT2.
Amino-acid sequence (126 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UQCC2?
The strongest Open Targets associations for UQCC2 are Isolated CoQ-cytochrome C reductase deficiency, neurodegenerative disease, celiac disease, eosinophil percentage of leukocytes and multiple sclerosis.
How long is the UQCC2 protein?
The Homo sapiens UQCC2 protein (UniProt Q9BRT2) is 126 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRT2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRT2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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