Migration and invasion enhancer 1 (MIEN1)
Homo sapiens — UniProt Q9BRT3
Data last refreshed: (UniProt release unknown)
Key facts
Migration and invasion enhancer 1 (MIEN1) is a protein from Homo sapiens identified by UniProt accession Q9BRT3, 115 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q9BRT3; gene symbol MIEN1.
- Organism: Homo sapiens.
- Length: 115 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cystatin C measurement and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Migration and invasion enhancer 1 |
|---|---|
| UniProt accession | Q9BRT3 |
| Gene | MIEN1 |
| Organism | Homo sapiens |
| Length | 115 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.18
- cystatin C measurement · score 0.09
- glomerular filtration rate · score 0.09
- creatinine measurement · score 0.09
- serum urea measurement · score 0.09
- cancer · score 0.09
- erythrocyte count · score 0.08
- ulcerative colitis · score 0.07
- neoplasm · score 0.07
- breast cancer · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRT3-F1 | alphafold | PREDICTED | 75.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRT3.
Amino-acid sequence (115 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIEN1?
The strongest Open Targets associations for MIEN1 are neurodegenerative disease, cystatin C measurement, glomerular filtration rate, creatinine measurement and serum urea measurement.
How long is the MIEN1 protein?
The Homo sapiens MIEN1 protein (UniProt Q9BRT3) is 115 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRT3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRT3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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