rRNA-processing protein UTP23 homolog (UTP23)
Homo sapiens — UniProt Q9BRU9
Data last refreshed: (UniProt release unknown)
Key facts
rRNA-processing protein UTP23 homolog (UTP23) is a protein from Homo sapiens identified by UniProt accession Q9BRU9, 249 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9BRU9; gene symbol UTP23.
- Organism: Homo sapiens.
- Length: 249 amino acids.
- Top disease associations (Open Targets): Cornelia de Lange syndrome, neurodegenerative disease and Mungan syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | rRNA-processing protein UTP23 homolog |
|---|---|
| UniProt accession | Q9BRU9 |
| Gene | UTP23 |
| Organism | Homo sapiens |
| Length | 249 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- Cornelia de Lange syndrome · score 0.53
- neurodegenerative disease · score 0.39
- Mungan syndrome · score 0.34
- colorectal cancer · score 0.20
- genetic disorder · score 0.17
- colorectal adenoma · score 0.16
- body height · score 0.13
- vital capacity · score 0.13
- heel bone mineral density · score 0.12
- smoking status measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRU9-F1 | alphafold | PREDICTED | 82.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRU9.
Amino-acid sequence (249 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UTP23?
The strongest Open Targets associations for UTP23 are Cornelia de Lange syndrome, neurodegenerative disease, Mungan syndrome, colorectal cancer and genetic disorder.
How long is the UTP23 protein?
The Homo sapiens UTP23 protein (UniProt Q9BRU9) is 249 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRU9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRU9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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