Sugar transporter SWEET1 (SLC50A1)
Homo sapiens — UniProt Q9BRV3
Data last refreshed: (UniProt release unknown)
Key facts
Sugar transporter SWEET1 (SLC50A1) is a protein from Homo sapiens identified by UniProt accession Q9BRV3, 221 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q9BRV3; gene symbol SLC50A1.
- Organism: Homo sapiens.
- Length: 221 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): serum alanine aminotransferase measurement, aspartate aminotransferase measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sugar transporter SWEET1 |
|---|---|
| UniProt accession | Q9BRV3 |
| Gene | SLC50A1 |
| Organism | Homo sapiens |
| Length | 221 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- serum alanine aminotransferase measurement · score 0.26
- aspartate aminotransferase measurement · score 0.22
- platelet count · score 0.16
- urinary albumin to creatinine ratio · score 0.15
- serum gamma-glutamyl transferase measurement · score 0.14
- urate measurement · score 0.14
- electrocardiography · score 0.14
- digit length ratio · score 0.13
- low density lipoprotein cholesterol measurement · score 0.12
- hematocrit · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRV3-F1 | alphafold | PREDICTED | 90.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRV3.
Amino-acid sequence (221 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC50A1?
The strongest Open Targets associations for SLC50A1 are serum alanine aminotransferase measurement, aspartate aminotransferase measurement, platelet count, urinary albumin to creatinine ratio and serum gamma-glutamyl transferase measurement.
How long is the SLC50A1 protein?
The Homo sapiens SLC50A1 protein (UniProt Q9BRV3) is 221 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRV3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRV3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.