Protein pelota homolog (PELO)
Homo sapiens — UniProt Q9BRX2
Data last refreshed: (UniProt release unknown)
Key facts
Protein pelota homolog (PELO) is a protein from Homo sapiens identified by UniProt accession Q9BRX2, 385 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q9BRX2; gene symbol PELO.
- Organism: Homo sapiens.
- Length: 385 amino acids.
- Top disease associations (Open Targets): reticulocyte count, reticulocyte measurement and Immature Reticulocyte Fraction Measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein pelota homolog |
|---|---|
| UniProt accession | Q9BRX2 |
| Gene | PELO |
| Organism | Homo sapiens |
| Length | 385 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.65
- reticulocyte measurement · score 0.64
- Immature Reticulocyte Fraction Measurement · score 0.60
- lymphocyte count · score 0.31
- low density lipoprotein cholesterol measurement · score 0.31
- type 2 diabetes mellitus · score 0.30
- total blood protein measurement · score 0.30
- C-reactive protein measurement · score 0.29
- apolipoprotein B measurement · score 0.28
- alkaline phosphatase measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRX2-F1 | alphafold | PREDICTED | 88.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRX2.
Amino-acid sequence (385 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PELO?
The strongest Open Targets associations for PELO are reticulocyte count, reticulocyte measurement, Immature Reticulocyte Fraction Measurement, lymphocyte count and low density lipoprotein cholesterol measurement.
How long is the PELO protein?
The Homo sapiens PELO protein (UniProt Q9BRX2) is 385 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRX2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRX2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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