Peroxiredoxin-like 2A (PRXL2A)
Homo sapiens — UniProt Q9BRX8
Data last refreshed: (UniProt release unknown)
Key facts
Peroxiredoxin-like 2A (PRXL2A) is a protein from Homo sapiens identified by UniProt accession Q9BRX8, 229 residues long. MolForge cross-references it against 1 known binders and 57 disease associations.
- UniProt accession: Q9BRX8; gene symbol PRXL2A.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, blood protein measurement and hematocrit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peroxiredoxin-like 2A |
|---|---|
| UniProt accession | Q9BRX8 |
| Gene | PRXL2A |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.31
- blood protein measurement · score 0.24
- hematocrit · score 0.17
- creatinine measurement · score 0.16
- cataract · score 0.15
- urate measurement · score 0.15
- systolic blood pressure · score 0.15
- cognitive function measurement · score 0.14
- hemoglobin measurement · score 0.14
- vitamin D measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRX8-F1 | alphafold | PREDICTED | 88.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRX8.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRXL2A?
The strongest Open Targets associations for PRXL2A are heel bone mineral density, blood protein measurement, hematocrit, creatinine measurement and cataract.
How long is the PRXL2A protein?
The Homo sapiens PRXL2A protein (UniProt Q9BRX8) is 229 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRX8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRX8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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