WD repeat domain-containing protein 83 (WDR83)
Homo sapiens — UniProt Q9BRX9
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat domain-containing protein 83 (WDR83) is a protein from Homo sapiens identified by UniProt accession Q9BRX9, 315 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q9BRX9; gene symbol WDR83.
- Organism: Homo sapiens.
- Length: 315 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, glioblastoma multiforme and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat domain-containing protein 83 |
|---|---|
| UniProt accession | Q9BRX9 |
| Gene | WDR83 |
| Organism | Homo sapiens |
| Length | 315 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- glioblastoma multiforme · score 0.29
- breast adenocarcinoma · score 0.29
- endometrial cancer · score 0.18
- alpha-mannosidosis · score 0.12
- syndromic intellectual disability · score 0.12
- attention deficit hyperactivity disorder · score 0.11
- Red cell distribution width · score 0.10
- familial juvenile hyperuricemic nephropathy type 1 · score 0.06
- nephrotic syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRX9-F1 | alphafold | PREDICTED | 93.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRX9.
Amino-acid sequence (315 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR83?
The strongest Open Targets associations for WDR83 are neurodegenerative disease, glioblastoma multiforme, breast adenocarcinoma, endometrial cancer and alpha-mannosidosis.
How long is the WDR83 protein?
The Homo sapiens WDR83 protein (UniProt Q9BRX9) is 315 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.