Zinc transporter ZIP3 (SLC39A3)
Homo sapiens — UniProt Q9BRY0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc transporter ZIP3 (SLC39A3) is a protein from Homo sapiens identified by UniProt accession Q9BRY0, 314 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9BRY0; gene symbol SLC39A3.
- Organism: Homo sapiens.
- Length: 314 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): neurodegenerative disease, Okt4 epitope deficiency and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc transporter ZIP3 |
|---|---|
| UniProt accession | Q9BRY0 |
| Gene | SLC39A3 |
| Organism | Homo sapiens |
| Length | 314 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.28
- Okt4 epitope deficiency · score 0.05
- bone density · score 0.04
- urate measurement · score 0.04
- combined immunodeficiency with skin granulomas · score 0.04
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- 22q11.2 deletion syndrome · score 0.03
- chronotype measurement · score 0.03
- eosinophil count · score 0.03
- hypertension · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BRY0-F1 | alphafold | PREDICTED | 81.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BRY0.
Amino-acid sequence (314 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC39A3?
The strongest Open Targets associations for SLC39A3 are neurodegenerative disease, Okt4 epitope deficiency, bone density, urate measurement and combined immunodeficiency with skin granulomas.
How long is the SLC39A3 protein?
The Homo sapiens SLC39A3 protein (UniProt Q9BRY0) is 314 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BRY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BRY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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