Endoplasmic reticulum resident protein 44 (ERP44)
Homo sapiens — UniProt Q9BS26
Data last refreshed: (UniProt release unknown)
Key facts
Endoplasmic reticulum resident protein 44 (ERP44) is a protein from Homo sapiens identified by UniProt accession Q9BS26, 406 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.
- UniProt accession: Q9BS26; gene symbol ERP44.
- Organism: Homo sapiens.
- Length: 406 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, insomnia and total blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Endoplasmic reticulum resident protein 44 |
|---|---|
| UniProt accession | Q9BS26 |
| Gene | ERP44 |
| Organism | Homo sapiens |
| Length | 406 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.33
- insomnia · score 0.22
- total blood protein measurement · score 0.22
- ganglion cell inner plexiform layer thickness measurement · score 0.19
- hematocrit · score 0.10
- macula measurement · score 0.07
- retinal layer thickness measurement · score 0.06
- Griscelli syndrome type 3 · score 0.05
- medical procedure · score 0.05
- acral peeling skin syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BS26-F1 | alphafold | PREDICTED | 89.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BS26.
Amino-acid sequence (406 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ERP44?
The strongest Open Targets associations for ERP44 are neurodegenerative disease, insomnia, total blood protein measurement, ganglion cell inner plexiform layer thickness measurement and hematocrit.
How long is the ERP44 protein?
The Homo sapiens ERP44 protein (UniProt Q9BS26) is 406 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BS26 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BS26 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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