A-kinase anchoring protein 19 (AKAP19)

About A-kinase anchoring protein 19

A-kinase anchoring protein 19 (AKAP19) is a protein from Homo sapiens identified by UniProt accession Q9BSF0, 95 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.

Target properties

Protein name	A-kinase anchoring protein 19
UniProt accession	Q9BSF0
Gene	AKAP19
Organism	Homo sapiens
Length	95 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (94)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.29
reticulocyte measurement · score 0.24
HbA1c measurement · score 0.22
diastolic blood pressure · score 0.17
self reported educational attainment · score 0.15
beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.06
familial isolated congenital asplenia · score 0.06
protein measurement · score 0.06
hemoglobin D disease · score 0.06
essential thrombocythemia · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BSF0-F1	alphafold	PREDICTED	71.28	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSF0.

Amino-acid sequence (95 residues)

MGCMKSKQTF PFPTIYEGEK QHESEEPFMP EERCLPRMAS PVNVKEEVKE PPGTNTVILE YAHRLSQDIL CDALQQWACN NIKYHDIPYI ESEGP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards