BTB/POZ domain-containing protein 10 (BTBD10)
Homo sapiens — UniProt Q9BSF8
Data last refreshed: (UniProt release unknown)
Key facts
BTB/POZ domain-containing protein 10 (BTBD10) is a protein from Homo sapiens identified by UniProt accession Q9BSF8, 475 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q9BSF8; gene symbol BTBD10.
- Organism: Homo sapiens.
- Length: 475 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, calcium measurement and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BTB/POZ domain-containing protein 10 |
|---|---|
| UniProt accession | Q9BSF8 |
| Gene | BTBD10 |
| Organism | Homo sapiens |
| Length | 475 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- calcium measurement · score 0.14
- hepatocellular carcinoma · score 0.07
- attention deficit hyperactivity disorder · score 0.05
- deafness · score 0.05
- schizophrenia 15 · score 0.04
- neoplasm · score 0.04
- X-linked dominant intellectual disability - epilepsy syndrome · score 0.04
- chronic obstructive pulmonary disease · score 0.04
- Autosomal recessive spastic paraplegia type 44 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BSF8-F1 | alphafold | PREDICTED | 68.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSF8.
Amino-acid sequence (475 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BTBD10?
The strongest Open Targets associations for BTBD10 are neurodegenerative disease, calcium measurement, hepatocellular carcinoma, attention deficit hyperactivity disorder and deafness.
How long is the BTBD10 protein?
The Homo sapiens BTBD10 protein (UniProt Q9BSF8) is 475 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BSF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BSF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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