Protease-associated domain-containing protein 1 (PRADC1)
Homo sapiens — UniProt Q9BSG0
Data last refreshed: (UniProt release unknown)
Key facts
Protease-associated domain-containing protein 1 (PRADC1) is a protein from Homo sapiens identified by UniProt accession Q9BSG0, 188 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9BSG0; gene symbol PRADC1.
- Organism: Homo sapiens.
- Length: 188 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, intelligence and mean arterial pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protease-associated domain-containing protein 1 |
|---|---|
| UniProt accession | Q9BSG0 |
| Gene | PRADC1 |
| Organism | Homo sapiens |
| Length | 188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.22
- intelligence · score 0.12
- mean arterial pressure · score 0.10
- MODY · score 0.08
- hyperproinsulinemia · score 0.06
- cognitive function measurement · score 0.05
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04
- Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.04
- 3-hydroxy-3-methylglutaryl-CoA synthase deficiency · score 0.04
- exercise-induced hyperinsulinism · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BSG0-F1 | alphafold | PREDICTED | 86.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSG0.
Amino-acid sequence (188 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRADC1?
The strongest Open Targets associations for PRADC1 are self reported educational attainment, intelligence, mean arterial pressure, MODY and hyperproinsulinemia.
How long is the PRADC1 protein?
The Homo sapiens PRADC1 protein (UniProt Q9BSG0) is 188 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BSG0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BSG0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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