Tripartite motif-containing protein 51 (TRIM51)
Homo sapiens — UniProt Q9BSJ1
Data last refreshed: (UniProt release unknown)
Key facts
Tripartite motif-containing protein 51 (TRIM51) is a protein from Homo sapiens identified by UniProt accession Q9BSJ1, 452 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9BSJ1; gene symbol TRIM51.
- Organism: Homo sapiens.
- Length: 452 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, melanoma and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tripartite motif-containing protein 51 |
|---|---|
| UniProt accession | Q9BSJ1 |
| Gene | TRIM51 |
| Organism | Homo sapiens |
| Length | 452 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- melanoma · score 0.07
- reticulocyte measurement · score 0.07
- blood coagulation disease · score 0.05
- coagulation protein disease · score 0.03
- high density lipoprotein cholesterol measurement · score 0.03
- leukocyte count · score 0.03
- cancer · score 0.02
- serum alanine aminotransferase measurement · score 0.02
- appendicular lean mass · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BSJ1-F1 | alphafold | PREDICTED | 86.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSJ1.
Amino-acid sequence (452 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TRIM51?
The strongest Open Targets associations for TRIM51 are neurodegenerative disease, melanoma, reticulocyte measurement, blood coagulation disease and coagulation protein disease.
How long is the TRIM51 protein?
The Homo sapiens TRIM51 protein (UniProt Q9BSJ1) is 452 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BSJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BSJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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