Zinc finger protein 577 (ZNF577)
Homo sapiens — UniProt Q9BSK1
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 577 (ZNF577) is a protein from Homo sapiens identified by UniProt accession Q9BSK1, 485 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9BSK1; gene symbol ZNF577.
- Organism: Homo sapiens.
- Length: 485 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cognitive domain measurement and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 577 |
|---|---|
| UniProt accession | Q9BSK1 |
| Gene | ZNF577 |
| Organism | Homo sapiens |
| Length | 485 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- cognitive domain measurement · score 0.23
- high density lipoprotein cholesterol measurement · score 0.12
- apolipoprotein A 1 measurement · score 0.10
- serum albumin measurement · score 0.07
- eosinophil count · score 0.07
- alcohol drinking · score 0.07
- blood protein measurement · score 0.07
- alcohol consumption measurement · score 0.07
- physical activity · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BSK1-F1 | alphafold | PREDICTED | 63.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSK1.
Amino-acid sequence (485 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF577?
The strongest Open Targets associations for ZNF577 are neurodegenerative disease, cognitive domain measurement, high density lipoprotein cholesterol measurement, apolipoprotein A 1 measurement and serum albumin measurement.
How long is the ZNF577 protein?
The Homo sapiens ZNF577 protein (UniProt Q9BSK1) is 485 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BSK1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BSK1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.