Phagosome assembly factor 1 (PHAF1)
Homo sapiens — UniProt Q9BSU1
Data last refreshed: (UniProt release unknown)
Key facts
Phagosome assembly factor 1 (PHAF1) is a protein from Homo sapiens identified by UniProt accession Q9BSU1, 422 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9BSU1; gene symbol PHAF1.
- Organism: Homo sapiens.
- Length: 422 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, body height and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phagosome assembly factor 1 |
|---|---|
| UniProt accession | Q9BSU1 |
| Gene | PHAF1 |
| Organism | Homo sapiens |
| Length | 422 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.27
- body height · score 0.22
- mean corpuscular hemoglobin · score 0.21
- hematological measurement · score 0.19
- mean reticulocyte volume · score 0.18
- erythrocyte count · score 0.12
- mean corpuscular hemoglobin concentration · score 0.11
- heel bone mineral density · score 0.04
- adolescent idiopathic scoliosis · score 0.04
- bone quantitative ultrasound measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BSU1-F1 | alphafold | PREDICTED | 86.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSU1.
Amino-acid sequence (422 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PHAF1?
The strongest Open Targets associations for PHAF1 are mean corpuscular volume, body height, mean corpuscular hemoglobin, hematological measurement and mean reticulocyte volume.
How long is the PHAF1 protein?
The Homo sapiens PHAF1 protein (UniProt Q9BSU1) is 422 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BSU1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BSU1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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