N-alpha-acetyltransferase 11 (NAA11)

Homo sapiens — UniProt Q9BSU3

Gene: NAA11Homo sapiensSwissProt reviewed

About N-alpha-acetyltransferase 11

N-alpha-acetyltransferase 11 (NAA11) is a protein from Homo sapiens identified by UniProt accession Q9BSU3, 229 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein nameN-alpha-acetyltransferase 11
UniProt accessionQ9BSU3
GeneNAA11
OrganismHomo sapiens
Length229 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (31)

Diseases linked to this target (Open Targets).

  • schizophrenia · score 0.45
  • wellbeing measurement · score 0.43
  • unipolar depression · score 0.38
  • attention deficit hyperactivity disorder · score 0.38
  • risk-taking behaviour · score 0.33
  • depressive symptom measurement · score 0.31
  • obsessive-compulsive disorder · score 0.30
  • bipolar disorder · score 0.30
  • Tourette syndrome · score 0.30
  • autism spectrum disorder · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BSU3-F1alphafoldPREDICTED79.40—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSU3.

Amino-acid sequence (229 residues)

MNIRNAQPDD LMNMQHCNLL CLPENYQMKY YLYHGLSWPQ LSYIAEDEDG KIVGYVLAKM EEEPDDVPHG HITSLAVKRS HRRLGLAQKL MDQASRAMIE NFNAKYVSLH VRKSNRPALH LYSNTLNFQI SEVEPKYYAD GEDAYAMKRD LSQMADELRR QMDLKKGGYV VLGSRENQET QGSTLSDSEE ACQQKNPATE ESGSDSKEPK ESVESTNVQD SSESSDSTS

Explore N-alpha-acetyltransferase 11 with MolForge

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Quick facts

UniProtQ9BSU3
GeneNAA11
OrganismHomo sapiens
Length229
Binders0
Diseases31
View on UniProt