Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 (CHCHD5)
Homo sapiens — UniProt Q9BSY4
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 (CHCHD5) is a protein from Homo sapiens identified by UniProt accession Q9BSY4, 110 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9BSY4; gene symbol CHCHD5.
- Organism: Homo sapiens.
- Length: 110 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, smoking behavior and smoking status measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 |
|---|---|
| UniProt accession | Q9BSY4 |
| Gene | CHCHD5 |
| Organism | Homo sapiens |
| Length | 110 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.11
- smoking behavior · score 0.11
- smoking status measurement · score 0.10
- neoplasm · score 0.03
- Obesity · score 0.02
- neuroticism measurement · score 0.02
- cancer · score 0.02
- small cell lung carcinoma · score 0.01
- Neoplasm of the lung · score 0.00
- adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BSY4-F1 | alphafold | PREDICTED | 66.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BSY4.
Amino-acid sequence (110 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHCHD5?
The strongest Open Targets associations for CHCHD5 are C-reactive protein measurement, smoking behavior, smoking status measurement, neoplasm and Obesity.
How long is the CHCHD5 protein?
The Homo sapiens CHCHD5 protein (UniProt Q9BSY4) is 110 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BSY4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BSY4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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