Nucleoporin NDC1 (NDC1)
Homo sapiens — UniProt Q9BTX1
Data last refreshed: (UniProt release unknown)
Key facts
Nucleoporin NDC1 (NDC1) is a protein from Homo sapiens identified by UniProt accession Q9BTX1, 674 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q9BTX1; gene symbol NDC1.
- Organism: Homo sapiens.
- Length: 674 amino acids.
- Top disease associations (Open Targets): HIV infection, influenza and viral disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleoporin NDC1 |
|---|---|
| UniProt accession | Q9BTX1 |
| Gene | NDC1 |
| Organism | Homo sapiens |
| Length | 674 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.54
- influenza · score 0.54
- viral disease · score 0.53
- Histiocytosis · score 0.37
- COVID-19 · score 0.37
- clear cell renal carcinoma · score 0.28
- low grade glioma · score 0.25
- breast adenocarcinoma · score 0.25
- ovarian cancer · score 0.23
- endometrial cancer · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BTX1-F1 | alphafold | PREDICTED | 75.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BTX1.
Amino-acid sequence (674 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NDC1?
The strongest Open Targets associations for NDC1 are HIV infection, influenza, viral disease, Histiocytosis and COVID-19.
How long is the NDC1 protein?
The Homo sapiens NDC1 protein (UniProt Q9BTX1) is 674 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BTX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BTX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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