Programmed cell death protein 10 (PDCD10)
Homo sapiens — UniProt Q9BUL8
Data last refreshed: (UniProt release unknown)
Key facts
Programmed cell death protein 10 (PDCD10) is a protein from Homo sapiens identified by UniProt accession Q9BUL8, 212 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.
- UniProt accession: Q9BUL8; gene symbol PDCD10.
- Organism: Homo sapiens.
- Length: 212 amino acids.
- Top disease associations (Open Targets): famililal cerebral cavernous malformations, neurodegenerative disease and cerebral cavernous malformation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Programmed cell death protein 10 |
|---|---|
| UniProt accession | Q9BUL8 |
| Gene | PDCD10 |
| Organism | Homo sapiens |
| Length | 212 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (120)
Diseases linked to this target (Open Targets).
- famililal cerebral cavernous malformations · score 0.66
- neurodegenerative disease · score 0.49
- cerebral cavernous malformation · score 0.46
- genetic disorder · score 0.40
- cerebral cavernous malformation 1 · score 0.34
- Cavernous Hemangioma · score 0.28
- Seizure · score 0.27
- Hemiparesis · score 0.27
- Cerebral arteriovenous malformation · score 0.27
- platelet count · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BUL8-F1 | alphafold | PREDICTED | 90.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BUL8.
Amino-acid sequence (212 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PDCD10?
The strongest Open Targets associations for PDCD10 are famililal cerebral cavernous malformations, neurodegenerative disease, cerebral cavernous malformation, genetic disorder and cerebral cavernous malformation 1.
How long is the PDCD10 protein?
The Homo sapiens PDCD10 protein (UniProt Q9BUL8) is 212 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BUL8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BUL8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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