Alpha-N-acetylgalactosaminide…

About Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5) is a protein from Homo sapiens identified by UniProt accession Q9BVH7, 336 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
UniProt accession	Q9BVH7
Gene	ST6GALNAC5
Organism	Homo sapiens
Length	336 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

gut microbiome measurement · score 0.32
alcohol drinking · score 0.26
pancreatic adenocarcinoma · score 0.21
multiple sclerosis · score 0.08
PHF-tau measurement · score 0.08
cognitive function measurement · score 0.04
Barrett's esophagus · score 0.03
body fat percentage · score 0.03
glioblastoma multiforme · score 0.03
central nervous system cancer · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BVH7-F1	alphafold	PREDICTED	81.05	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BVH7.

Amino-acid sequence (336 residues)

MKTLMRHGLA VCLALTTMCT SLLLVYSSLG GQKERPPQQQ QQQQQQQQQA SATGSSQPAA ESSTQQRPGV PAGPRPLDGY LGVADHKPLK MHCRDCALVT SSGHLLHSRQ GSQIDQTECV IRMNDAPTRG YGRDVGNRTS LRVIAHSSIQ RILRNRHDLL NVSQGTVFIF WGPSSYMRRD GKGQVYNNLH LLSQVLPRLK AFMITRHKML QFDELFKQET GKDRKISNTW LSTGWFTMTI ALELCDRINV YGMVPPDFCR DPNHPSVPYH YYEPFGPDEC TMYLSHERGR KGSHHRFITE KRVFKNWART FNIHFFQPDW KPESLAINHP ENKPVF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (ST6GALNAC5)