Transmembrane emp24 domain-containing protein 9 (TMED9)
Homo sapiens — UniProt Q9BVK6
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane emp24 domain-containing protein 9 (TMED9) is a protein from Homo sapiens identified by UniProt accession Q9BVK6, 235 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9BVK6; gene symbol TMED9.
- Organism: Homo sapiens.
- Length: 235 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, monoclonal B-cell lymphocytosis and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane emp24 domain-containing protein 9 |
|---|---|
| UniProt accession | Q9BVK6 |
| Gene | TMED9 |
| Organism | Homo sapiens |
| Length | 235 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- monoclonal B-cell lymphocytosis · score 0.11
- mathematical ability · score 0.11
- self reported educational attainment · score 0.10
- hepatocellular carcinoma · score 0.08
- neoplasm · score 0.04
- cancer · score 0.03
- leukocyte count · score 0.03
- clear cell renal carcinoma · score 0.01
- diffuse large B-cell lymphoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BVK6-F1 | alphafold | PREDICTED | 83.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BVK6.
Amino-acid sequence (235 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMED9?
The strongest Open Targets associations for TMED9 are neurodegenerative disease, monoclonal B-cell lymphocytosis, mathematical ability, self reported educational attainment and hepatocellular carcinoma.
How long is the TMED9 protein?
The Homo sapiens TMED9 protein (UniProt Q9BVK6) is 235 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BVK6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BVK6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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