TIMELESS-interacting protein (TIPIN)

Homo sapiens — UniProt Q9BVW5

Gene: TIPINHomo sapiensSwissProt reviewed

About TIMELESS-interacting protein

TIMELESS-interacting protein (TIPIN) is a protein from Homo sapiens identified by UniProt accession Q9BVW5, 301 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.

Target properties

Protein nameTIMELESS-interacting protein
UniProt accessionQ9BVW5
GeneTIPIN
OrganismHomo sapiens
Length301 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (52)

Diseases linked to this target (Open Targets).

  • breast adenocarcinoma · score 0.25
  • ovarian cancer · score 0.18
  • mean corpuscular volume · score 0.17
  • mathematical ability · score 0.15
  • Red cell distribution width · score 0.14
  • body mass index · score 0.14
  • mean corpuscular hemoglobin concentration · score 0.14
  • self reported educational attainment · score 0.13
  • mean corpuscular hemoglobin · score 0.13
  • insomnia measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BVW5-F1alphafoldPREDICTED66.85—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BVW5.

Amino-acid sequence (301 residues)

MLEPQENGVI DLPDYEHVED ETFPPFPPPA SPERQDGEGT EPDEESGNGA PVRVPPKRTV KRNIPKLDAQ RLISERGLPA LRHVFDKAKF KGKGHEAEDL KMLIRHMEHW AHRLFPKLQF EDFIDRVEYL GSKKEVQTCL KRIRLDLPIL HEDFVSNNDE VAENNEHDVT STELDPFLTN LSESEMFASE LSRSLTEEQQ QRIERNKQLA LERRQAKLLS NSQTLGNDML MNTPRAHTVE EVNTDEDQKE ESNGLNEDIL DNPCNDAIAN TLNEEETLLD QSFKNVQQQL DATSRNITEA R

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Quick facts

UniProtQ9BVW5
GeneTIPIN
OrganismHomo sapiens
Length301
Binders0
Diseases52
View on UniProt