Protein lifeguard 2 (FAIM2)
Homo sapiens — UniProt Q9BWQ8
Data last refreshed: (UniProt release unknown)
Key facts
Protein lifeguard 2 (FAIM2) is a protein from Homo sapiens identified by UniProt accession Q9BWQ8, 316 residues long. MolForge cross-references it against 0 known binders and 155 disease associations.
- UniProt accession: Q9BWQ8; gene symbol FAIM2.
- Organism: Homo sapiens.
- Length: 316 amino acids.
- Top disease associations (Open Targets): body mass index, urate measurement and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein lifeguard 2 |
|---|---|
| UniProt accession | Q9BWQ8 |
| Gene | FAIM2 |
| Organism | Homo sapiens |
| Length | 316 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (155)
Diseases linked to this target (Open Targets).
- body mass index · score 0.40
- urate measurement · score 0.38
- type 2 diabetes mellitus · score 0.37
- body weight · score 0.36
- lean body mass · score 0.36
- creatinine measurement · score 0.34
- blood urea nitrogen measurement · score 0.34
- serum urea measurement · score 0.32
- neurodegenerative disease · score 0.31
- fat body mass · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BWQ8-F1 | alphafold | PREDICTED | 77.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BWQ8.
Amino-acid sequence (316 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAIM2?
The strongest Open Targets associations for FAIM2 are body mass index, urate measurement, type 2 diabetes mellitus, body weight and lean body mass.
How long is the FAIM2 protein?
The Homo sapiens FAIM2 protein (UniProt Q9BWQ8) is 316 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BWQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BWQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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