Receptor for retinol uptake STRA6 (STRA6)
Homo sapiens — UniProt Q9BX79
Data last refreshed: (UniProt release unknown)
Key facts
Receptor for retinol uptake STRA6 (STRA6) is a protein from Homo sapiens identified by UniProt accession Q9BX79, 667 residues long. MolForge cross-references it against 0 known binders and 308 disease associations.
- UniProt accession: Q9BX79; gene symbol STRA6.
- Organism: Homo sapiens.
- Length: 667 amino acids.
- Top disease associations (Open Targets): Matthew-Wood syndrome, microphthalmia, isolated, with coloboma and microphthalmia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Receptor for retinol uptake STRA6 |
|---|---|
| UniProt accession | Q9BX79 |
| Gene | STRA6 |
| Organism | Homo sapiens |
| Length | 667 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (308)
Diseases linked to this target (Open Targets).
- Matthew-Wood syndrome · score 0.82
- microphthalmia, isolated, with coloboma · score 0.67
- microphthalmia · score 0.66
- anophthalmia-microphthalmia syndrome · score 0.46
- cystatin C measurement · score 0.25
- thyroid gland adenocarcinoma · score 0.23
- glomerular filtration rate · score 0.22
- breast adenocarcinoma · score 0.21
- genetic disorder · score 0.19
- blood protein measurement · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BX79-F1 | alphafold | PREDICTED | 77.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BX79.
Amino-acid sequence (667 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STRA6?
The strongest Open Targets associations for STRA6 are Matthew-Wood syndrome, microphthalmia, isolated, with coloboma, microphthalmia, anophthalmia-microphthalmia syndrome and cystatin C measurement.
How long is the STRA6 protein?
The Homo sapiens STRA6 protein (UniProt Q9BX79) is 667 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BX79 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BX79 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.