Succinate receptor 1 (SUCNR1)
Homo sapiens — UniProt Q9BXA5
Data last refreshed: (UniProt release unknown)
Key facts
Succinate receptor 1 (SUCNR1) is a protein from Homo sapiens identified by UniProt accession Q9BXA5, 334 residues long. MolForge cross-references it against 1 known binders and 213 disease associations.
- UniProt accession: Q9BXA5; gene symbol SUCNR1.
- Organism: Homo sapiens.
- Length: 334 amino acids.
- Approved drugs acting on it (DrugCentral): Succinic Acid.
- Top disease associations (Open Targets): hair shape measurement, balding measurement and androgenetic alopecia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Succinate receptor 1 |
|---|---|
| UniProt accession | Q9BXA5 |
| Gene | SUCNR1 |
| Organism | Homo sapiens |
| Length | 334 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). Approved drug exists
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Approved drugs acting on this target (1)
Approved drugs whose DrugCentral mechanism of action is this protein, most potent first.
Disease associations (213)
Diseases linked to this target (Open Targets).
- hair shape measurement · score 0.40
- balding measurement · score 0.39
- androgenetic alopecia · score 0.35
- diffuse plaque measurement · score 0.29
- vital capacity · score 0.29
- alopecia · score 0.28
- glioblastoma multiforme · score 0.24
- ovarian cancer · score 0.23
- PHF-tau measurement · score 0.13
- neurodegenerative disease · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXA5-F1 | alphafold | PREDICTED | 87.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXA5.
Amino-acid sequence (334 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which approved drugs target SUCNR1?
DrugCentral lists 1 approved drug whose mechanism of action is SUCNR1: Succinic Acid.
Which diseases are associated with SUCNR1?
The strongest Open Targets associations for SUCNR1 are hair shape measurement, balding measurement, androgenetic alopecia, diffuse plaque measurement and vital capacity.
How long is the SUCNR1 protein?
The Homo sapiens SUCNR1 protein (UniProt Q9BXA5) is 334 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXA5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXA5 — predicted 3D structure (CC BY 4.0)
- DrugCentral — approved drugs and mechanism-of-action links (CC BY-SA 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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