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Testis-specific serine/threonine-protein kinase 6 (TSSK6)

Homo sapiens — UniProt Q9BXA6

Gene: TSSK6Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Testis-specific serine/threonine-protein kinase 6 (TSSK6) is a protein from Homo sapiens identified by UniProt accession Q9BXA6, 273 residues long. MolForge cross-references it against 0 known binders and 147 disease associations.

  • UniProt accession: Q9BXA6; gene symbol TSSK6.
  • Organism: Homo sapiens.
  • Length: 273 amino acids.
  • Top disease associations (Open Targets): Red cell distribution width, platelet count and eosinophil count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTestis-specific serine/threonine-protein kinase 6
UniProt accessionQ9BXA6
GeneTSSK6
OrganismHomo sapiens
Length273 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (147)

Diseases linked to this target (Open Targets).

  • Red cell distribution width · score 0.25
  • platelet count · score 0.15
  • eosinophil count · score 0.15
  • breast carcinoma · score 0.14
  • schizophrenia · score 0.13
  • body height · score 0.13
  • reticulocyte count · score 0.12
  • azoospermia · score 0.11
  • male infertility with teratozoospermia due to single gene mutation · score 0.10
  • anorexia nervosa · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXA6-F1alphafoldPREDICTED93.46—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXA6.

Amino-acid sequence (273 residues)

MSGDKLLSEL GYKLGRTIGE GSYSKVKVAT SKKYKGTVAI KVVDRRRAPP DFVNKFLPRE LSILRGVRHP HIVHVFEFIE VCNGKLYIVM EAAATDLLQA VQRNGRIPGV QARDLFAQIA GAVRYLHDHH LVHRDLKCEN VLLSPDERRV KLTDFGFGRQ AHGYPDLSTT YCGSAAYASP EVLLGIPYDP KKYDVWSMGV VLYVMVTGCM PFDDSDIAGL PRRQKRGVLY PEGLELSERC KALIAELLQF SPSARPSAGQ VARNCWLRAG DSG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TSSK6?

The strongest Open Targets associations for TSSK6 are Red cell distribution width, platelet count, eosinophil count, breast carcinoma and schizophrenia.

How long is the TSSK6 protein?

The Homo sapiens TSSK6 protein (UniProt Q9BXA6) is 273 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXA6
GeneTSSK6
OrganismHomo sapiens
Length273
Binders0
Diseases147
View on UniProt